Target Details
UniProt ACO43613
Gene SymbolHCRTR1
Protein NameOrexin/Hypocretin receptor type 1
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00001 (7tm_1)
UniProt
Summary
  • Multi-target molecules 3,881
  • Clinical molecules 0
  • Avg pChEMBL 7.32
KEGG Pathways (2)
Top Co-occurrence Targets
Active Molecules (3,881)
InChIKey pChEMBL Type Targets Clinical
VDPZWYVAUUMDAS 10.2 Ki 2 —
KQBPICDNFNTNHQ 10.0 IC50 2 —
SPVLNBKCMBRTPX 10.0 IC50 2 —
XHZWYNZVBWJJCI 9.9 Ki 2 —
DBOQFZYFAREFRH 9.8 Ki 2 —
AHSULABMWQXHMG 9.7 IC50 2 —
VSLUJTNAZDNCRC 9.5 Ki 2 —
VYUBRYYCCNWARR 9.5 IC50 2 —
ZGEVFIAJYRECKD 9.5 IC50 2 —
ZJXIUGNEAIHSBI 9.5 Ki 2 —
WFWYBEKBFWVQBF 9.4 Ki 2 —
ARZIDKSCLITHPX 9.4 Ki 2 —
DLTFUAAXCYAOLA 9.4 IC50 2 —
HVXSUZLOKRFHBC 9.4 Ki 2 —
HVXSUZLOKRFHBC 9.4 Ki 2 —
JQAUBUKTUAAFTO 9.4 IC50 2 —
XJCZLPCRYACTDC 9.4 Ki 2 —
OXSFCPCDXHDPHW 9.3 Ki 2 —
PNGWMHMVJINNEB 9.3 IC50 2 —
PQIZGRDRKSOBSA 9.3 IC50 2 —
YHWXLTYWQSZIKW 9.3 IC50 2 —
JJALNSGVCOGWGJ 9.2 IC50 2 —
OAFQCEGEQYCFCR 9.2 IC50 2 —
QJIOQYNIYMMLJX 9.2 IC50 2 —
AEZZJXJIJFSUEM 9.2 IC50 2 —
DPAIDVFQHYLKSX 9.2 IC50 2 —
FEJNEXSKTFURIP 9.2 IC50 2 —
PNRIERFKCYVVOG 9.2 IC50 2 —
SHBXIINOQJVTRR 9.2 IC50 2 —
UMVDIYYEKWWNEU 9.2 IC50 2 —
YUVVLHJTSJCFEC 9.2 Ki 2 —
HKMZXBJJLIWIFY 9.1 Ki 2 —
JNJHLMLNEZQKOC 9.1 Ki 2 —
KETDPAVPRYOAGQ 9.1 IC50 2 —
FJESWXBARXLORJ 9.1 Ki 2 —
AQFPGDOPAWNDQW 9.1 IC50 2 —
BRMIJZHNESDJJS 9.1 IC50 2 —
HOHXELLMHKNVOC 9.1 IC50 2 —
KYRKCIQITPJUGV 9.1 IC50 2 —
OZQQWERPXKWLAA 9.1 IC50 2 —
TUAKDXOHUHYBRM 9.1 IC50 2 —
LAPXEGYDIDMVOP 9.1 IC50 2 —
GIWGNHDZELXXNP 9.1 IC50 2 —
PYKRMGBCBZXQMO 9.1 Ki 2 —
BIYHTTUWIYFGHN 9.1 IC50 2 —
DJPWHBDTSPGVAZ 9.1 IC50 2 —
FCVGUKJNRFNLDS 9.1 IC50 2 —
FDXRERSZBCJENM 9.1 IC50 2 —
FKHQMNLZLWPYFA 9.1 IC50 2 —
JOFVCMFATFJQCO 9.1 IC50 2 —
2D structure