Target Details
| UniProt AC | O14936 |
|---|---|
| Gene Symbol | CASK |
| Protein Name | Peripheral plasma membrane protein CASK |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00625 (Guanylate_kin) PF02828 (L27) PF00595 (PDZ) PF00069 (Pkinase) PF07653 (SH3_2) |
Summary
- Multi-target molecules 14
- Clinical molecules 6
- Avg pChEMBL 6.64
KEGG Pathways (1)
Associated Diseases (2)
Active Molecules (14)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
HKSZLNNOFSGOKW
|
7.7 | Kd | 408 | — | |
OVPNQJVDAFNBDN
|
7.6 | Kd | 44 | Yes | |
XYASHXPUZJDWIO
|
7.4 | Kd | 7 | — | |
JRNJNYBQQYBCLE
|
7.2 | Kd | 40 | Yes | |
KTEIFNKAUNYNJU
|
6.8 | Kd | 114 | — | |
VDKBGBCLPKTOGS
|
6.8 | Kd | 2 | — | |
UIARLYUEJFELEN
|
6.5 | Kd | 289 | Yes | |
OUSFTKFNBAZUKL
|
6.4 | Kd | 58 | Yes | |
NXSJMRCTGYTSTK
|
6.3 | Kd | 200 | — | |
UBPYILGKFZZVDX
|
6.1 | Kd | 130 | Yes | |
QQWUGDVOUVUTOY
|
6.0 | Kd | 231 | Yes | |
IVVSBEQDCAZLFY
|
6.0 | IC50 | 333 | — | |
KHVVJKLNKLQLJZ
|
6.0 | IC50 | 288 | — | |
MAHFVAHPQSLLJF
|
6.0 | IC50 | 288 | — |