AP3B1 — MultiTargetDB

Target Details

UniProt AC	`O00203`
Gene Symbol	AP3B1
Protein Name	AP-3 complex subunit beta-1
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF01602 (Adaptin_N) PF14796 (AP3B1_C) PF24080 (AP3B1_C_2) PF14797 (SEEEED)

Summary

Multi-target molecules 3
Clinical molecules 0
Avg pChEMBL 6.92

KEGG Pathways (1)

Lysosome biogenesis

Associated Diseases (1)

Hermansky-Pudlak syndrome

Top Co-occurrence Targets

SUPT16H 3 shared
AP1M1 3 shared
TUBGCP2 3 shared
SRSF7 3 shared
EFTUD2 3 shared
NUMA1 3 shared
NOLC1 3 shared
CHD4 3 shared
EIF3A 3 shared
U2AF1 3 shared

Active Molecules (3)

InChIKey	pChEMBL	Type	Targets	Clinical
`MWKSRKSEWLRPBL`	7.3	Kd	1075	—
`AAAQFGUYHFJNHI`	7.2	IC50	252	—
`ZCCPLJOKGAACRT`	6.2	Kd	599	—