Target Details
| UniProt AC | K9N7C7 |
|---|---|
| Gene Symbol | rep |
| Protein Name | Replicase polyprotein 1ab |
| Organism | Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) |
| Entry Name | |
| Organism Category | Pathogen |
| Pfam Domains | PF13087 (AAA_12) PF13604 (AAA_30) PF16251 (bCoV_NAB) PF11501 (bCoV_NSP1) PF11633 (bCoV_SUD_M) PF06471 (CoV_ExoN) PF06460 (CoV_Methyltr_2) PF09401 (CoV_NSP10) PF20631 (CoV_NSP13_1B) PF20633 (CoV_NSP13_stalk) PF20632 (CoV_NSP13_ZBD) PF19215 (CoV_NSP15_C) PF19216 (CoV_NSP15_M) PF19219 (CoV_NSP15_N) PF19212 (CoV_NSP2_C) PF19211 (CoV_NSP2_N) PF19218 (CoV_NSP3_C) PF16348 (CoV_NSP4_C) PF19217 (CoV_NSP4_N) PF19213 (CoV_NSP6) PF08716 (CoV_NSP7) PF08717 (CoV_NSP8) PF08710 (CoV_NSP9) PF08715 (CoV_peptidase) PF06478 (CoV_RPol_N) PF01661 (Macro) PF05409 (Peptidase_C30) PF00680 (RdRP_1) |
Summary
- Multi-target molecules 2
- Clinical molecules 0
- Avg pChEMBL 6.28
Top Co-occurrence Targets
- orf1a 2 shared
Active Molecules (2)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
AVMDEKFUKVZQPM
|
6.4 | IC50 | 2 | — | |
PJEUBFINPIVQHS
|
6.2 | IC50 | 2 | — |