Target Details
UniProt ACD2K2A8
Gene SymbolNS4A
Protein NameN/A
OrganismHepacivirus hominis
Entry Name
Organism Category Pathogen
Pfam Domains PF01006 (HCV_NS4a)
UniProt
Summary
  • Multi-target molecules 650
  • Clinical molecules 0
  • Avg pChEMBL 7.83
Top Co-occurrence Targets
  • NS3 647 shared
  • 210 shared
  • NS3/4A 205 shared
  • 49 shared
  • 31 shared
  • 30 shared
  • 10 shared
  • 5 shared
  • 5 shared
  • 3 shared
Active Molecules (650)
InChIKey pChEMBL Type Targets Clinical
FIGPTAABOPCRSH 11.0 Ki 2 —
GBJKXZJNFVRHCK 11.0 IC50 2 —
SQQGVKCGPPDKIF 10.7 IC50 2 —
YZEYKJWFONXNBD 10.7 Ki 3 —
IEBGGVPRMXUKNF 10.5 IC50 2 —
LXSRYYXUUWUCEM 10.4 IC50 2 —
IBHJUUGEQZOQPH 10.3 IC50 3 —
KQSGUUWGOHGMQH 10.3 IC50 2 —
NIIHAMOFPVWTDC 10.3 IC50 2 —
PYPJBTBCRUERPE 10.3 IC50 2 —
CXFHUKRXFUSTMU 10.2 IC50 3 —
FCSRQPLWGJGTGW 10.2 Ki 3 —
OBMNJSNZOWALQB 10.1 IC50 3 —
WGZBAYGWEODRMQ 10.1 IC50 2 —
LXVFWKZFKJJWAG 10.1 IC50 2 —
BWVKIFXNVRCJTL 10.0 Ki 3 —
DULIAOKIHPSTBZ 10.0 Ki 3 —
FSFUVODFJRFRKJ 10.0 Ki 3 —
HDWIOVGJBLMAHV 10.0 Ki 3 —
IHXGLDBKRROHDN 10.0 Ki 4 —
JDMPXCANLSMISU 10.0 Ki 3 —
NSICSOQWNRELKK 10.0 Ki 4 —
SMGNMBKPAWFKGH 10.0 Ki 3 —
VOMDFEZIJGRATE 10.0 Ki 3 —
YXTMRVYVGOSPFS 10.0 Ki 3 —
LKEIANAQOBMEEA 9.8 Ki 3 —
MLSQGNCUYAMAHD 9.8 Ki 4 —
DIXUBOKOVNHCON 9.7 Ki 3 —
DOPFAJXYFJSQLF 9.7 Ki 3 —
FEBJFCFXFXZCLS 9.7 Ki 3 —
LCAFUXRRYVUDAO 9.7 Ki 3 —
NWXBVPNHAHFNDG 9.7 Ki 3 —
RKXAXJJYZWSYOP 9.7 Ki 3 —
VZVDPMKXCRVDCZ 9.7 Ki 3 —
XYPHLGHQUSHJJC 9.7 Ki 3 —
ZVTDLPBHTSMEJZ 9.7 IC50 3 —
CVFQOKIBZTWREC 9.6 Ki 4 —
DOPFAJXYFJSQLF 9.5 Ki 3 —
LYPMUUHUNIGEOB 9.5 Ki 4 —
WQSVAGOHZLUGGP 9.5 Ki 3 —
QTMQMPYQUFCQIC 9.5 Ki 3 —
JTZZSQYMACOLNN 9.4 Ki 6 —
PJZPDFUUXKKDNB 9.3 IC50 3 —
CFMGTKRBVVZVBF 9.3 IC50 4 —
KVJXHBSWSKTCIN 9.3 Ki 3 —
NZPMMQUIHRLKAM 9.3 Ki 2 —
PFORZALCOLIZSP 9.3 Ki 3 —
RWMPLRLPTAINLR 9.3 Ki 3 —
YBOIHIZQJVYWPZ 9.3 Ki 3 —
AMHREMDNJWVSKV 9.2 Ki 3 —
2D structure