Target Details
UniProt ACB0BL08
Gene SymboldfrA17
Protein Namedihydrofolate reductase
OrganismEscherichia coli
Entry Name
Organism Category Pathogen
Pfam Domains PF00186 (DHFR_1)
UniProt
Summary
  • Multi-target molecules 223
  • Clinical molecules 1
  • Avg pChEMBL 7.55
Top Co-occurrence Targets
Active Molecules (223)
InChIKey pChEMBL Type Targets Clinical
RWFMFIBVNGVPBZ 6.7 Ki 2 —
NSFQURBMDUNXNO 6.7 Ki 2 —
UMCWAPSUYPKLED 6.7 Ki 2 —
OZRNSSUDZOLUSN 6.6 Kd 2 —
YYJWQABXDCUJEF 6.6 IC50 3 —
BAZGOWDIOHAUFL 6.6 Ki 2 —
NNYBKFNWRMTXCR 6.6 IC50 3 —
AWRSFYZUXOPKGI 6.6 Ki 2 —
ZZPQXWUFUDPLIE 6.6 Ki 2 —
FTOBOFSPQDHWIA 6.6 Ki 2 —
MOQBRTUVUCVOLA 6.6 Ki 2 —
YOQRIBLPMWWYIV 6.6 Ki 2 —
YZGBAURBIITWIY 6.6 Ki 3 —
OHSQJDNOJOOLNZ 6.5 Ki 2 —
XEJJIPLFLDZYDR 6.5 Ki 2 —
KMWVEFVCYFWEAK 6.5 IC50 2 —
HQJJMAGMUHCNRA 6.5 Ki 2 —
RBGDXCYSDUHWLX 6.5 Ki 2 —
MSTNYGQPCMXVAQ 6.5 Kd 3 —
OWESLNUTAHNAGR 6.5 IC50 3 —
UOJFGEAPSYQDIP 6.5 IC50 4 —
AVRPDIOCAAWICH 6.5 IC50 4 —
OXQILUPNLGVNIF 6.5 IC50 2 —
VFZAHIZMEQZSOQ 6.5 Ki 2 —
ZGWAEUUYBLJLPE 6.5 Ki 2 —
LZPWIAMCHOARHU 6.5 Ki 2 —
QBQBQHCSEMOJAW 6.5 Ki 3 —
KNMBSJCWXZMBIJ 6.5 Ki 2 —
MSWFGUWKPUQAJI 6.5 Ki 2 —
QYTFIBBOLLCUOK 6.5 Ki 2 —
HIMYFSLMYAONKN 6.4 Ki 2 —
XJLXINKUBYWONI 6.4 Kd 3 —
BZYVACJRYZJYKG 6.4 IC50 4 —
KQNSOABYMIHDJR 6.4 IC50 2 —
IPNRBRMBXBDEFP 6.4 Ki 2 —
KRFLPUDDWLIYEZ 6.4 Ki 2 —
UVFCOEHLSTZCHI 6.4 IC50 2 —
ARHDQCNCQPWFCT 6.4 Ki 3 —
HNWYPMQIUVCRED 6.4 IC50 3 —
XTCMQKRJGTYGIJ 6.4 Ki 2 —
BYDBBHVBHPKCHX 6.4 IC50 2 —
HLVXCAKKBNEDDK 6.4 IC50 3 —
WFWMBUFEDMTUNR 6.4 IC50 3 —
IMJCIHFHJWNKIN 6.4 IC50 3 —
CYWWLUGRQFFCDK 6.3 Ki 2 —
DNBQLUIAJYMPNG 6.3 Ki 2 —
LDJJOBOSGIJBCF 6.3 Ki 2 —
PYTYTJYUKZXVCB 6.3 Ki 2 —
INKUWRYTZMLPQI 6.3 IC50 2 —
PTWJNRZKGULCMJ 6.3 IC50 4 —
2D structure