Target Details
| UniProt AC | A5X5Y0 |
|---|---|
| Gene Symbol | HTR3E |
| Protein Name | 5-hydroxytryptamine receptor 3E |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF02931 (Neur_chan_LBD) PF02932 (Neur_chan_memb) |
Summary
- Multi-target molecules 183
- Clinical molecules 6
- Avg pChEMBL 7.84
KEGG Pathways (3)
Active Molecules (183)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
DNJXPDYLZIVHDP
|
6.7 | IC50 | 5 | — | |
WEOIHIYCKWSSBW
|
6.7 | Ki | 5 | — | |
AOOSJYIINXVNHV
|
6.7 | Ki | 16 | — | |
LIIRNJNGOKYCIP
|
6.7 | Ki | 5 | — | |
IUNFWMWQNWQIFS
|
6.6 | Ki | 5 | — | |
DTOKLFDSWKGLOX
|
6.6 | Ki | 5 | — | |
OZINHCFSCQEUPW
|
6.6 | Ki | 5 | — | |
YJNPVKYWRQNPBX
|
6.5 | IC50 | 5 | — | |
ZSJNJAJDBNFVCA
|
6.5 | Ki | 5 | — | |
MVWVFYHBGMAFLY
|
6.4 | Ki | 31 | Yes | |
QZUDBNBUXVUHMW
|
6.4 | Ki | 39 | Yes | |
NKPRIPDEFRADKU
|
6.4 | Ki | 6 | — | |
PNROIWQNPITPBR
|
6.4 | Ki | 5 | — | |
PKQYVFHRKFDVCH
|
6.4 | Ki | 5 | — | |
OBWCQARWOVVGRJ
|
6.3 | Ki | 5 | — | |
JTLCTTWVUAIQHD
|
6.3 | IC50 | 17 | Yes | |
CEUORZQYGODEFX
|
6.3 | Ki | 31 | — | |
UVOCSZKGWJOKNN
|
6.3 | Ki | 11 | — | |
LGWFAAILRNJWJB
|
6.3 | Ki | 6 | — | |
MMSIHQRSTJAVNZ
|
6.2 | Ki | 6 | — | |
VYZPEWUEPPGXGA
|
6.2 | Ki | 5 | — | |
IPKZCLGGYKRDES
|
6.2 | Ki | 6 | — | |
UZJWAFOJOSGEKL
|
6.2 | IC50 | 15 | — | |
CXDMUUBLDHSHNL
|
6.2 | Ki | 6 | — | |
ALPVAQHXSGKIAL
|
6.2 | Ki | 6 | — | |
RHFLZSUIVOSCKT
|
6.2 | Ki | 6 | — | |
BGMSTNYJYPSLHN
|
6.2 | IC50 | 4 | — | |
PDOCNPCPPLPXRV
|
6.1 | Ki | 5 | — | |
CFHPNABTZSOBQJ
|
6.1 | Ki | 5 | — | |
ILEIGUXOYKZHRK
|
6.0 | Ki | 5 | — | |
IEUXRHDPSSNADT
|
6.0 | Kd | 5 | — | |
VGFALHATLLBXIT
|
6.0 | Ki | 5 | — | |
YOGJZQGRTVMCPY
|
6.0 | IC50 | 17 | — |