Target Details
UniProt ACA3EZI9
Gene SymbolNS3
Protein NameGenome polyprotein
OrganismHepacivirus hominis
Entry Name
Organism Category Pathogen
Pfam Domains PF07652 (Flavi_DEAD) PF22027 (NS3_helicase_C) PF02907 (Peptidase_S29)
UniProt
Summary
  • Multi-target molecules 670
  • Clinical molecules 0
  • Avg pChEMBL 7.83
Top Co-occurrence Targets
  • NS4A 647 shared
  • 210 shared
  • NS3/4A 205 shared
  • 49 shared
  • 30 shared
  • 29 shared
  • ELANE 13 shared
  • 10 shared
  • CTRC 9 shared
  • 7 shared
Active Molecules (670)
InChIKey pChEMBL Type Targets Clinical
FWXGYYOJJUMIFD 7.8 Ki 2 —
JXYSYDXTCQGOTL 7.8 Ki 3 —
MMEBEYJGRMEXOT 7.8 IC50 4 —
SGHJJLBGKZIPSW 7.8 IC50 4 —
WWSVSJDVHSBDBB 7.8 IC50 2 —
DCZOEBDBHRUWIP 7.8 Ki 2 —
HOZOPPUBYQVCPM 7.8 IC50 3 —
KWAMFFSETRPXMK 7.8 Ki 2 —
BFDKJVNQRNACCV 7.8 Ki 2 —
BYPMXQSCKKNTGN 7.8 IC50 3 —
VRKCKWLSJXJKQS 7.8 Ki 3 —
VXKCZMDSTKEAJX 7.8 IC50 2 —
XFXQDMHDNGOKBW 7.8 IC50 2 —
DEOAHOSUZUPNCA 7.8 Ki 2 —
YTOCFEHRXHCGHM 7.8 IC50 3 —
YMHQYWPVQDRYSQ 7.8 IC50 3 —
SAFGREOPRVGQQX 7.7 Ki 2 —
ZRQUXAFGWKDGRE 7.7 IC50 2 —
PMYKJCMKUQGKCJ 7.7 IC50 2 —
QHUFHOWZHGDXDX 7.7 Ki 2 —
QTUUBAKAOZLXGQ 7.7 Ki 2 —
AFTKZUHBECRIPD 7.7 IC50 4 —
ANELJGXPPPDOLX 7.7 Ki 2 —
DTAGYFFAIVVJHG 7.7 IC50 4 —
GHODPLAVFAKUTP 7.7 Ki 2 —
JRBOXXSEYWPYMG 7.7 IC50 4 —
NAEFTBYPSLMAJV 7.7 IC50 4 —
NFHAZLUKVPHWIG 7.7 Ki 2 —
QDLVNWRFJITDTF 7.7 IC50 4 —
QUTJDLPIJGFVTJ 7.7 IC50 4 —
UVNAIHPALNWIGA 7.7 IC50 4 —
XQWARQVHEJRBID 7.7 IC50 4 —
BHALKRHIAOUWNH 7.7 IC50 3 —
OCYIAXNHVLIDIT 7.7 Ki 2 —
QFVVLWTXDCYIMN 7.7 IC50 4 —
TURVLKLYHQZYDB 7.7 Ki 2 —
WRQGKPHOSPVHIN 7.7 Ki 2 —
FTPCVQUWCWXUHD 7.6 IC50 2 —
DOEZXCZJNCFNGG 7.6 IC50 3 —
VZQBLIGJOFRBEW 7.6 IC50 3 —
BXZYHWGQDBDZKB 7.6 IC50 4 —
GQDQSRGJEOLULH 7.6 Ki 2 —
JFFCCDKBNGGOOE 7.6 IC50 4 —
LFKITAOQQDIAJF 7.6 Ki 2 —
MJXQFUHPNRVFRD 7.6 IC50 4 —
NSGBTQBHUVVQQK 7.6 IC50 4 —
RFBAMGIPTJOMSX 7.6 IC50 4 —
UOZVLIAVHBKHOK 7.6 IC50 4 —
UVTRVCYUHKMBNY 7.6 Ki 2 —
YBTBVSQNDKHMPU 7.6 IC50 4 —
2D structure