Target Details
UniProt ACA3EZI9
Gene SymbolNS3
Protein NameGenome polyprotein
OrganismHepacivirus hominis
Entry Name
Organism Category Pathogen
Pfam Domains PF07652 (Flavi_DEAD) PF22027 (NS3_helicase_C) PF02907 (Peptidase_S29)
UniProt
Summary
  • Multi-target molecules 670
  • Clinical molecules 0
  • Avg pChEMBL 7.83
Top Co-occurrence Targets
  • NS4A 647 shared
  • 210 shared
  • NS3/4A 205 shared
  • 49 shared
  • 30 shared
  • 29 shared
  • ELANE 13 shared
  • 10 shared
  • CTRC 9 shared
  • 7 shared
Active Molecules (670)
InChIKey pChEMBL Type Targets Clinical
BIOAIESFQROFGZ 8.5 Ki 2 —
CFMGTKRBVVZVBF 8.5 IC50 4 —
DXPGMMXRSXDODO 8.5 Ki 2 —
HGMYODZJZPUWRC 8.5 IC50 4 —
HPKSTJTTXUFYNM 8.5 IC50 4 —
HQLIOGBJINMZFY 8.5 IC50 4 —
IQGJMNCUACIRBB 8.5 IC50 4 —
IWLXLASMFWNYHL 8.5 IC50 4 —
JTZZSQYMACOLNN 8.5 IC50 2 —
NEVFFERKSBAOKS 8.5 Ki 2 —
OALAYFQOTXVKEU 8.5 IC50 4 —
RJVIUDPSQFFUFS 8.5 Ki 2 —
RMVRFXPWQGESLH 8.5 Ki 2 —
SSFQPBNIKXPGCC 8.5 IC50 4 —
ZZDPVPHOHNYTAU 8.5 IC50 4 —
YCYCBCSJYGZXLL 8.5 Ki 3 —
RWXBAQMWNLSEBP 8.5 IC50 4 —
UTASHZYEMHIPHH 8.5 IC50 3 —
CTSWGNQIQFMNNJ 8.5 IC50 4 —
JCCKYOXTHKQKBS 8.5 IC50 3 —
KCVVJXPLYSFXRJ 8.5 IC50 4 —
NJWQXXNLNZOZAW 8.5 IC50 4 —
PVCSQCFJSXLCFF 8.5 Ki 2 —
RDHZGKIYONRFGL 8.5 IC50 4 —
RWXBAQMWNLSEBP 8.5 IC50 4 —
SJNFJPFMHJLWNR 8.5 IC50 4 —
XEPCTFXTGPAHEJ 8.5 IC50 4 —
DLORRRHWKGMQHQ 8.4 IC50 3 —
IQVIVUQYANERMA 8.4 IC50 3 —
OAMLETSZKAKGGK 8.4 IC50 3 —
BMBDQEBZOWGMBB 8.4 IC50 3 —
PCWBICPLNKRDCZ 8.4 IC50 3 —
QNRBXDCBCPJVRB 8.4 IC50 3 —
SOAJNGWSIIAAQL 8.4 IC50 3 —
YEXVOZNCLYKDPL 8.4 IC50 3 —
BQYZLLOXLULFFT 8.4 Ki 2 —
CFGJXJWENUPGMZ 8.4 IC50 4 —
FRGWURYHPUCUDI 8.4 IC50 2 —
HOTYIQRBUUORJU 8.4 IC50 2 —
MKZMSPZMLQRZHL 8.4 IC50 2 —
RTDZYXVTDSBNJN 8.4 IC50 4 —
XKBNMUGCTFZZNE 8.4 IC50 2 —
XRRYEGIOXDSKKH 8.4 IC50 3 —
YROXKHKMMWFHOY 8.4 IC50 2 —
HSAIGVGBYWBEFK 8.4 Ki 2 —
HOXBFIPKPBODHA 8.4 IC50 3 —
IAWKVVNKOOMFDE 8.4 IC50 4 —
MKIVCMAHUCRSFE 8.4 Ki 2 —
NZMACXRFJSDAOU 8.4 Ki 2 —
GGDBDVHXMMLBAO 8.3 IC50 4 —
2D structure