Target Details
UniProt ACA3EZI9
Gene SymbolNS3
Protein NameGenome polyprotein
OrganismHepacivirus hominis
Entry Name
Organism Category Pathogen
Pfam Domains PF07652 (Flavi_DEAD) PF22027 (NS3_helicase_C) PF02907 (Peptidase_S29)
UniProt
Summary
  • Multi-target molecules 670
  • Clinical molecules 0
  • Avg pChEMBL 7.83
Top Co-occurrence Targets
  • NS4A 647 shared
  • 210 shared
  • NS3/4A 205 shared
  • 49 shared
  • 30 shared
  • 29 shared
  • ELANE 13 shared
  • 10 shared
  • CTRC 9 shared
  • 7 shared
Active Molecules (670)
InChIKey pChEMBL Type Targets Clinical
LKRUWLUIDVGBFA 7.1 Ki 2 —
KOKNYEMMHABSGG 7.1 Ki 4 —
PNJHHRKKKXJSKO 7.1 IC50 4 —
SKBNPHMFNYRNKO 7.1 IC50 4 —
UKBFCXQFCCHEMD 7.1 Ki 2 —
WTSRZSYGCVJMOO 7.1 Ki 2 —
XVOMSIXPGRHYAB 7.1 Ki 2 —
CQSMRQTYHTYLOS 7.0 Ki 2 —
JHJYWDWXFAVMPG 7.0 IC50 3 —
UINMWOYMKDJTCK 7.0 IC50 4 —
YHPGGDKFNAIFIV 7.0 IC50 3 —
IWMOWNMRTCQZIR 7.0 Ki 3 —
IYWRCNFZPNEADN 7.0 IC50 2 —
VMGAVHOARRCARD 7.0 IC50 4 —
ZCDDKCMUQMFSAF 7.0 IC50 4 —
DBUOUSUVJFJQEU 7.0 IC50 3 —
ANWXAHDHVAGJFL 7.0 Ki 2 —
DCTIRYQEVHXMIQ 7.0 Ki 2 —
GEYRWZXROAGFKI 7.0 Ki 2 —
IRCSMPPIHNRCHT 7.0 IC50 4 —
JETFGTQZGKPRJS 7.0 Ki 2 —
JRCBDJUHNKIGTH 7.0 Ki 2 —
LIVZWBUJKWXSLM 7.0 Ki 3 —
QWYPRFOWQNPOKD 7.0 Ki 2 —
XERCXZZGTKXDMV 7.0 Ki 2 —
FSLSRHRBOXSDLM 7.0 Ki 2 —
ADJFHPNBBGXXKC 7.0 Ki 3 —
HNPLEXIJHRPWSQ 7.0 Ki 2 —
NHMXXVRJRISJLC 7.0 Ki 3 —
URHRYXMPBLWUFT 7.0 Ki 2 —
PATSIXADBDLBCE 6.9 Ki 2 —
PZEWIJLQRKOFCH 6.9 IC50 2 —
UEDMZRPUOVWABU 6.9 Ki 2 —
HPRDONOVNQOEIV 6.9 Ki 2 —
DWKJSANEXFKFAV 6.9 Ki 2 —
MTBDXMMFZOUHMX 6.9 IC50 2 —
OMZOSIDRSAKTBR 6.9 Ki 2 —
SPAZLRZRWNMBFN 6.9 IC50 3 —
VUSOSFZGBGAREA 6.9 IC50 3 —
PUGIRQCTBMBEPT 6.9 Ki 3 —
NZADTYIDOHSVBG 6.8 Ki 2 —
OKJZIZVNNATHRC 6.8 Ki 2 —
CZLOOGYQRKSADJ 6.8 Ki 2 —
ORFFWAWVEJAVBU 6.8 Ki 2 —
UCCKMSDPSUCKKP 6.8 Ki 2 —
HMGWJLLQHXADPW 6.8 Ki 2 —
GKQOINRSDGCLBX 6.8 Ki 3 —
JXIYRLUFEDRYKF 6.8 IC50 2 —
XOZFQDAJQXJTIQ 6.8 Ki 2 —
FYLYAHCSDRMYNB 6.8 Ki 2 —
2D structure