Molecule Details
| InChIKey | ZZWWXIBKLBMSCS-FQEVSTJZSA-N |
|---|---|
| Canonical SMILES | COc1ccccc1[C@H](Cn1c(=O)n(C(C)(C)C(=O)O)c(=O)c2c(C)c(-c3ncco3)sc21)OC1CCOCC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.55 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB16166 |
|---|---|
| Drug Name | Firsocostat |
| CAS Number | 1434635-54-7 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Firsocostat is under investigation in clinical trial NCT02781584 (Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)). |
Categories: Acids, Acyclic Butyrates Enzyme Inhibitors Fatty Acids Fatty Acids, Volatile Lipids Pyrimidines Sulfur Compounds
Cross-references: CHEMBL3407547 ChemSpider: 58789974 ZINC: ZINC000207531097