Molecule Details
InChIKeyZZTMFGIGOADCFX-UHFFFAOYSA-N
Canonical SMILESCCNC(=O)c1cn2ncnc(Nc3cc(C(=O)NOC)ccc3C)c2c1C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.16
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB06940
Drug NameN-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide
CAS Numbernan
Groups experimental
ATC Codes nan
DescriptionN-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide is a solid. This compound belongs to the pyrrolotriazines. These are compounds containing a pyrrolotriazine moiety, which consists of a pyrrole ring fused to a triazine ring. N-ethyl-4-{[5-(met...

Cross-references: BindingDB: 20649 CHEMBL252128 ChemSpider: 8310006 PDB: 279 PubChem:10134493 PubChem:99443411 ZINC: ZINC000006718471
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q16539 MAPK14 Homo sapiens Human PF00069 8.5 IC50 ChEMBL;BindingDB
Q15759 MAPK11 Homo sapiens Human PF00069 7.8 IC50 ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q16539 MAPK14 Mitogen-activated protein kinase 14 binder targets