Molecule Details
InChIKeyZZJLMZYUGLJBSO-LAEOZQHASA-N
Canonical SMILESC[C@H](N)C(=O)N1C[C@H](CCCB(O)O)[C@](N)(C(=O)O)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.8
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB15286
Drug NameNumidargistat
CAS Number2095732-06-0
Groups investigational
ATC Codes nan
DescriptionCB-1158 is under investigation in clinical trial NCT03910530 (A Study of INCMGA00012, INCB001158, and the Combination in Japanese Participants With Advanced Solid Tumors).

Categories: Enzyme Inhibitors
Cross-references: ChemSpider: 72379905
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P05089 ARG1 Homo sapiens Human PF00491 7.1 IC50 ChEMBL;BindingDB
P78540 ARG2 Homo sapiens Human PF00491 6.5 IC50 ChEMBL;BindingDB