Molecule Details
| InChIKey | ZYXHQIPQIKTEDI-UHFFFAOYSA-N |
|---|---|
| Compound Name | Lusaperidone |
| Canonical SMILES | Cc1nc2ccccn2c(=O)c1CCN1CCc2oc3ccccc3c2C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.27 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB06553 |
|---|---|
| Drug Name | R107474 |
| CAS Number | 214548-46-6 |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Cross-references: BindingDB: 50403744 CHEMBL162501 ChemSpider: 2308142 ZINC: ZINC000001903948
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P08913 | ADRA2A | Homo sapiens | Human | PF00001 | 9.3 | IC50 | ChEMBL;BindingDB |
| P18825 | ADRA2C | Homo sapiens | Human | PF00001 | 8.8 | IC50 | ChEMBL;BindingDB |
| P18089 | ADRA2B | Homo sapiens | Human | PF00001 | 8.6 | IC50 | ChEMBL;BindingDB |
| P35348 | ADRA1A | Homo sapiens | Human | PF00001 | 6.5 | IC50 | ChEMBL;BindingDB |