Molecule Details
| InChIKey | ZYXAFPZQDYBFBQ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 5-(4-((4-(1-methylpiperidin-4-yl)phenyl)amino)-1,3,5-triazin-2-yl)-2-((tetrahydro-2H-pyran-4-yl)oxy)benzonitrile |
| Canonical SMILES | CN1CCC(c2ccc(Nc3ncnc(-c4ccc(OC5CCOCC5)c(C#N)c4)n3)cc2)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.92 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q14164 | IKBKE | Homo sapiens | Human | PF00069 PF18394 PF18396 | 8.5 | IC50 | BindingDB |
| O60674 | JAK2 | Homo sapiens | Human | PF18379 PF18377 PF17887 PF07714 PF21990 | 6.2 | IC50 | BindingDB |
| Q9UHD2 | TBK1 | Homo sapiens | Human | PF00069 PF18394 PF18396 | 6.0 | IC50 | ChEMBL;BindingDB |