Molecule Details
InChIKeyZYTFPHRVOZXPGZ-UHFFFAOYSA-N
Compound Name2-[[5-(3-methyl-2H-indazol-5-yl)-3-pyridinyl]oxy]ethanamine
Canonical SMILESCc1n[nH]c2ccc(-c3cncc(OCCN)c3)cc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)30
Pfam Stratification Homologous
Avg pChEMBL6.84
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (30)
Target Gene Organism Category Pfam pChEMBL Type Source
P49760 CLK2 Homo sapiens Human PF00069 8.0 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 8.0 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.7 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 7.7 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 7.6 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 7.5 Ki ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 7.4 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 7.3 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.3 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 7.0 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.9 Ki ChEMBL
Q86V86 PIM3 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 6.8 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.6 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 6.6 Ki ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.5 Ki ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 6.4 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.3 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q13554 CAMK2B Homo sapiens Human PF08332 PF00069 6.2 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.2 Ki ChEMBL
Q5VT25 CDC42BPA Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 6.2 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.2 Ki ChEMBL
Q13237 PRKG2 Homo sapiens Human PF00027 PF00069 6.1 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL