Molecule Details
| InChIKey | ZXVNMYWKKDOREA-UHFFFAOYSA-N |
|---|---|
| Canonical SMILES | Cc1cc(CC(=O)O)n(C)c1C(=O)c1ccc(Cl)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.46 |
| Source | BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB04828 |
|---|---|
| Drug Name | Zomepirac |
| CAS Number | 33369-31-2 |
| Groups | approved withdrawn |
| ATC Codes | M01AB04 |
| Description | Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions. The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983. |
Categories: Acetic Acid Derivatives and Related Substances Agents causing hyperkalemia Agents that produce hypertension Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Antiinflammatory and Antirheumatic Products Antiinflammatory and Antirheumatic Products, Non-Steroids Antirheumatic Agents Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Substrates Musculo-Skeletal System Nephrotoxic agents Non COX-2 selective NSAIDS Peripheral Nervous System Agents Sensory System Agents
Cross-references: BindingDB: 50027952 ChEBI: 35859 CHEMBL19490 ChemSpider: 5531 PDB: ZOM PharmGKB: PA166049188 PubChem:5733 PubChem:46504549 RxCUI: 39994 Wikipedia: Zomepirac ZINC: ZINC000000057537