Molecule Details
| InChIKey | ZXOKHOODFVNZIC-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(1-(4-cyanobenzyl)piperidin-4-yl)-6-(4-(4-cyanophenoxy) piperidine-1-carbonyl)nicotinamide |
| Canonical SMILES | N#Cc1ccc(CN2CCC(NC(=O)c3ccc(C(=O)N4CCC(Oc5ccc(C#N)cc5)CC4)nc3)CC2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 7 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.32 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (7)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O43741 | PRKAB2 | Homo sapiens | Human | PF16561 PF04739 | 6.3 | IC50 | ChEMBL |
| P54619 | PRKAG1 | Homo sapiens | Human | PF00571 | 6.3 | IC50 | ChEMBL |
| P54646 | PRKAA2 | Homo sapiens | Human | PF16579 PF21147 PF00069 | 6.3 | IC50 | ChEMBL |
| Q13131 | PRKAA1 | Homo sapiens | Human | PF16579 PF21147 PF00069 | 6.3 | IC50 | ChEMBL |
| Q9UGI9 | PRKAG3 | Homo sapiens | Human | PF00571 | 6.3 | IC50 | ChEMBL |
| Q9UGJ0 | PRKAG2 | Homo sapiens | Human | PF00571 | 6.3 | IC50 | ChEMBL |
| Q9Y478 | PRKAB1 | Homo sapiens | Human | PF16561 PF04739 | 6.3 | IC50 | ChEMBL |