Molecule Details
| InChIKey | ZXFALDNPMLUADA-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-[4-(10H-imidazo[1,2-b][2]benzazepin-4-yl)-2,6-dimethylpiperazin-1-yl]propanoic acid |
| Canonical SMILES | CC1CN(C2=Cc3ccccc3Cn3ccnc32)CC(C)N1CCC(=O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.03 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P35367 | HRH1 | Homo sapiens | Human | PF00001 | 7.7 | Ki | ChEMBL;BindingDB |
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 7.4 | Ki | ChEMBL;BindingDB |
| P28335 | HTR2C | Homo sapiens | Human | PF00001 | 6.8 | Ki | ChEMBL;BindingDB |
| P41595 | HTR2B | Homo sapiens | Human | PF00001 | 6.2 | Ki | ChEMBL;BindingDB |