Molecule Details
| InChIKey | ZWUCWBYYVLQXEP-UHFFFAOYSA-N |
|---|---|
| Compound Name | 7-(1h-Benzimidazol-7-Yl)-N-(3,4,5-Trimethoxyphenyl)-1,3-Benzoxazol-2-Amine |
| Canonical SMILES | COc1cc(Nc2nc3cccc(-c4cccc5[nH]cnc45)c3o2)cc(OC)c1OC |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.05 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15349 | RPS6KA2 | Homo sapiens | Human | PF00069 PF00433 | 8.4 | IC50 | ChEMBL |
| P51812 | RPS6KA3 | Homo sapiens | Human | PF00069 PF00433 | 7.2 | IC50 | BindingDB |
| O60674 | JAK2 | Homo sapiens | Human | PF18379 PF18377 PF17887 PF07714 PF21990 | 6.3 | IC50 | ChEMBL;BindingDB |
| O14965 | AURKA | Homo sapiens | Human | PF00069 | 6.2 | IC50 | ChEMBL;BindingDB |