Molecule Details
| InChIKey | ZWIGVNWZHBPXNS-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-(4-(4-methoxybenzoyl) piperidine-1-carbonyl)-N-(1-(4-(trifluoromethoxy) benzyl)piperidin-4-yl)nicotinamide |
| Canonical SMILES | COc1ccc(C(=O)C2CCN(C(=O)c3ccc(C(=O)NC4CCN(Cc5ccc(OC(F)(F)F)cc5)CC4)cn3)CC2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 7 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.09 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (7)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O43741 | PRKAB2 | Homo sapiens | Human | PF16561 PF04739 | 6.1 | IC50 | ChEMBL |
| P54619 | PRKAG1 | Homo sapiens | Human | PF00571 | 6.1 | IC50 | ChEMBL |
| P54646 | PRKAA2 | Homo sapiens | Human | PF16579 PF21147 PF00069 | 6.1 | IC50 | ChEMBL |
| Q13131 | PRKAA1 | Homo sapiens | Human | PF16579 PF21147 PF00069 | 6.1 | IC50 | ChEMBL |
| Q9UGI9 | PRKAG3 | Homo sapiens | Human | PF00571 | 6.1 | IC50 | ChEMBL |
| Q9UGJ0 | PRKAG2 | Homo sapiens | Human | PF00571 | 6.1 | IC50 | ChEMBL |
| Q9Y478 | PRKAB1 | Homo sapiens | Human | PF16561 PF04739 | 6.1 | IC50 | ChEMBL |