3-(3,4-dimethoxyphenyl)-5-N-(1-methylpiperidin-4-yl)-6-phenylpyrazolo[1,5-a]pyrimidine-5,7-diamine

InChIKey	`ZVVQDNWRXSSQDL-UHFFFAOYSA-N`
Compound Name	3-(3,4-dimethoxyphenyl)-5-N-(1-methylpiperidin-4-yl)-6-phenylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Canonical SMILES	`COc1ccc(-c2cnn3c(N)c(-c4ccccc4)c(NC4CCN(C)CC4)nc23)cc1OC`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.42
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P07949	RET	Homo sapiens	Human	PF00028 PF07714 PF17756 PF17812 PF17813 PF22540	7.5	IC50	ChEMBL;BindingDB
P33176	KIF5B	Homo sapiens	Human	PF00225	7.5	IC50	ChEMBL
Q16204	CCDC6	Homo sapiens	Human	PF09755	7.2	IC50	ChEMBL;BindingDB