Molecule Details
| InChIKey | ZUXRUQOEFBOTGF-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[[3-chloro-4-(trifluoromethoxy)phenyl]methyl]-3-fluoro-4-(1,3-thiazol-2-ylsulfamoyl)benzamide |
| Canonical SMILES | O=C(NCc1ccc(OC(F)(F)F)c(Cl)c1)c1ccc(S(=O)(=O)Nc2nccs2)c(F)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.14 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9NY46 | SCN3A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 8.0 | IC50 | ChEMBL |
| P35498 | SCN1A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 7.7 | IC50 | ChEMBL |
| Q15858 | SCN9A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 6.5 | IC50 | ChEMBL |
| Q99250 | SCN2A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 6.4 | IC50 | ChEMBL |