Molecule Details
| InChIKey | ZUGQSSCMJHOUMY-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(1,3-benzodioxol-5-ylmethyl)-1-(1,3-thiazol-2-yl)-2H-chromeno[2,3-c]pyrrol-9-one |
| Canonical SMILES | O=c1c2ccccc2oc2c(Cc3ccc4c(c3)OCO4)[nH]c(-c3nccs3)c12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.19 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O76074 | PDE5A | Homo sapiens | Human | PF01590 PF00233 | 8.2 | IC50 | ChEMBL;BindingDB |
| P16499 | PDE6A | Homo sapiens | Human | PF01590 PF00233 | 7.2 | IC50 | ChEMBL;BindingDB |
| Q9Y233 | PDE10A | Homo sapiens | Human | PF01590 PF00233 | 6.8 | IC50 | ChEMBL;BindingDB |
| O00408 | PDE2A | Homo sapiens | Human | PF01590 PF00233 | 6.4 | IC50 | ChEMBL;BindingDB |