Molecule Details
| InChIKey | ZRQMUCDHVVOENY-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-pentylurea |
| Canonical SMILES | CCCCCNC(=O)/N=C(\N)NCCCc1sc(N)nc1C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 17 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 9.37 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (17)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P08173 | CHRM4 | Homo sapiens | Human | PF00001 | 10.3 | Kd | ChEMBL |
| P07550 | ADRB2 | Homo sapiens | Human | PF00001 | 10.2 | Kd | ChEMBL |
| P08588 | ADRB1 | Homo sapiens | Human | PF00001 | 10.1 | Kd | ChEMBL |
| P21917 | DRD4 | Homo sapiens | Human | PF00001 | 10.1 | Kd | ChEMBL |
| P08908 | HTR1A | Homo sapiens | Human | PF00001 | 10.1 | Kd | ChEMBL |
| P35372 | OPRM1 | Homo sapiens | Human | PF00001 | 10.1 | Kd | ChEMBL |
| P08172 | CHRM2 | Homo sapiens | Human | PF00001 | 10.0 | Kd | ChEMBL |
| P20309 | CHRM3 | Homo sapiens | Human | PF00001 | 9.9 | Kd | ChEMBL |
| P11229 | CHRM1 | Homo sapiens | Human | PF00001 | 9.8 | Kd | ChEMBL |
| P08912 | CHRM5 | Homo sapiens | Human | PF00001 | 9.7 | Kd | ChEMBL |
| P21918 | DRD5 | Homo sapiens | Human | PF00001 | 9.6 | Kd | ChEMBL |
| P35348 | ADRA1A | Homo sapiens | Human | PF00001 | 9.6 | Kd | ChEMBL |
| P08913 | ADRA2A | Homo sapiens | Human | PF00001 | 9.2 | Kd | ChEMBL |
| P25021 | HRH2 | Homo sapiens | Human | PF00001 | 8.3 | Ki | ChEMBL;BindingDB |
| P21728 | DRD1 | Homo sapiens | Human | PF00001 | 8.1 | Kd | ChEMBL |
| P35462 | DRD3 | Homo sapiens | Human | PF00001 | 7.8 | Ki | ChEMBL;BindingDB |
| P14416 | DRD2 | Homo sapiens | Human | PF00001 | 6.3 | Ki | ChEMBL;BindingDB |