N'-[5-(4-chloro-5-piperazin-1-yl-3-propan-2-yl-1H-pyrrolo[2,3-c]pyridin-2-yl)-3-methoxy-2-pyridinyl]methanimidamide

InChIKey	`ZRIMLXQGHRELEP-UHFFFAOYSA-N`
Compound Name	N'-[5-(4-chloro-5-piperazin-1-yl-3-propan-2-yl-1H-pyrrolo[2,3-c]pyridin-2-yl)-3-methoxy-2-pyridinyl]methanimidamide
Canonical SMILES	`COc1cc(-c2[nH]c3cnc(N4CCNCC4)c(Cl)c3c2C(C)C)c[nH]/c1=N\C=N`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	8.08
Source	BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9NYK1	TLR7	Homo sapiens	Human	PF13855 PF01582	9.2	IC50	BindingDB
Q9NR97	TLR8	Homo sapiens	Human	PF13855 PF01582	8.8	IC50	BindingDB
Q9NR96	TLR9	Homo sapiens	Human	PF18837 PF13516 PF13855 PF01582	6.2	IC50	BindingDB