Molecule Details
InChIKeyZQVQTUFEKLITNT-UHFFFAOYSA-N
Compound Nameethyl 5-amino-8-carbamoyl-3-oxo-7-thiophen-2-yl-2-(thiophen-2-ylmethylidene)-7H-[1,3]thiazolo[3,2-a]pyridine-6-carboxylate
Canonical SMILESCCOC(=O)C1=C(N)n2c(sc(=Cc3cccs3)c2=O)=C(C(N)=O)C1c1cccs1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Homologous
Avg pChEMBL6.12
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
Q96SB4 SRPK1 Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.2 Ki ChEMBL
Q8IW41 MAPKAPK5 Homo sapiens Human PF00069 6.2 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q86V86 PIM3 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q9H4B4 PLK3 Homo sapiens Human PF00069 PF00659 6.1 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9UBE8 NLK Homo sapiens Human PF00069 6.0 Ki ChEMBL