Molecule Details
InChIKeyZQUSFAUAYSEREK-WKILWMFISA-N
Canonical SMILESCOc1nccc(-c2c(-c3ccc(F)cc3)ncn2[C@H]2CC[C@H](O)CC2)n1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.32
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P45984 MAPK9 Homo sapiens Human PF00069 8.3 IC50 ChEMBL;BindingDB
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 7.7 IC50 ChEMBL;BindingDB
P48730 CSNK1D Homo sapiens Human PF00069 7.6 Ki ChEMBL
Q15759 MAPK11 Homo sapiens Human PF00069 7.4 IC50 ChEMBL;BindingDB
Q16539 MAPK14 Homo sapiens Human PF00069 7.4 IC50 ChEMBL;BindingDB
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 7.1 IC50 ChEMBL;BindingDB
P17252 PRKCA Homo sapiens Human PF00130 PF00168 PF00069 PF00433 7.1 IC50 ChEMBL;BindingDB
P18505 GABRB1 Homo sapiens Human PF02931 PF02932 7.1 pIC50 TTD_MultiTarget
P48729 CSNK1A1 Homo sapiens Human PF00069 6.3 Ki ChEMBL