Molecule Details
InChIKeyZQTKOYMWCCSKON-XKXNWSITSA-N
Canonical SMILESCC(C)c1ccccc1[C@@H]1CCCN1C1CC2(CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(NC[C@H]5CC[C@](C)(O)CC5)c([N+](=O)[O-])c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.68
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB18753
Drug NameSonrotoclax
CAS Number2383086-06-2
Groups investigational
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 567800 CHEMBL5314951 ChemSpider: 129309008 PDB: 98I
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P10415 BCL2 Homo sapiens Human PF00452 PF02180 9.6 IC50 ChEMBL;BindingDB
Q07817 BCL2L1 Homo sapiens Human PF00452 PF02180 7.7 IC50 ChEMBL;BindingDB