Molecule Details
| InChIKey | ZQFNDBISEYQVRR-LOSJGSFVSA-N |
|---|---|
| Compound Name | Mizacorat |
| Canonical SMILES | CC(C)[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2c(cnn2-c2ccc(=O)n(C)c2)c1)c1ccccc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.5 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB21458 |
|---|---|
| Drug Name | Mizacorat |
| CAS Number | 1893415-00-3 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Mizacorat is a small molecule drug. The usage of the INN stem '-corat' in the name indicates that Mizacorat is a glucocorticoid receptor agonist. Mizacorat is under investigation in clinical trial NCT04556760 (Study to Assess the Effect on Glucose Homeostasis of Two Dose Levels of AZD9567, Compared ... |
Categories: Heterocyclic Compounds, Fused-Ring Pyrazoles
Cross-references: BindingDB: 332659 CHEMBL4207852 PDB: B9W
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P04150 | NR3C1 | Glucocorticoid receptor | modulator | targets |