1-[4-[(2,4-Diaminopyrido[3,2-d]pyrimidin-6-yl)methyl-prop-2-ynyl-amino]phenyl]-2,2,2-trifluoro-ethanone

InChIKey	`ZPVABTSOZGBWAC-UHFFFAOYSA-N`
Compound Name	1-[4-[(2,4-Diaminopyrido[3,2-d]pyrimidin-6-yl)methyl-prop-2-ynyl-amino]phenyl]-2,2,2-trifluoro-ethanone
Canonical SMILES	`C#CCN(Cc1ccc2nc(N)nc(N)c2n1)c1ccc(C(=O)C(F)(F)F)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.09
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q07422		Toxoplasma gondii	Pathogen	PF00186 PF00303	7.3	IC50	ChEMBL;BindingDB
P07807	DFR1	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	Pathogen	PF00186	6.9	IC50	ChEMBL;BindingDB