InChIKey	ZPEIMTDSQAKGNT-UHFFFAOYSA-N
Compound Name	Chlorpromazine
Canonical SMILES	CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc21
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	35
Pfam Stratification	Cross-Family
Avg pChEMBL	7.16
Source	BindingDB;ChEMBL;TTD_MultiTarget

DrugBank ID	DB00477
Drug Name	Chlorpromazine
CAS Number	50-53-3
Groups	approved investigational vet_approved
ATC Codes	N05AA01
Description	The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an anti...

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Categories: Adrenergic Antagonists Adrenergic alpha-1 Receptor Antagonists Adrenergic alpha-Antagonists Agents producing tachycardia Agents that produce hypertension Agents that reduce seizure threshold Anticholinergic Agents Antidepressive Agents Antiemetics Antipsychotic Agents Antipsychotic Agents (First Generation [Typical]) Autonomic Agents BSEP/ABCB11 Inhibitors Central Nervous System Agents Central Nervous System Depressants Cholinesterase Inhibitors Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (moderate) Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP2E1 Inhibitors Cytochrome P-450 CYP2E1 Inhibitors (strength unknown) Cytochrome P-450 CYP3A Inducers Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inducers Cytochrome P-450 CYP3A4 Inducers (strength unknown) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A4 Substrates (strength unknown) Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dopamine Agents Dopamine Antagonists Dopamine D2 Receptor Antagonists Drugs causing inadvertant photosensitivity Drugs that are Mainly Renally Excreted Gastrointestinal Agents Heterocyclic Compounds, Fused-Ring Histamine Antagonists Histamine H1 Antagonists Hyperglycemia-Associated Agents Hypotensive Agents Moderate Risk QTc-Prolonging Agents Muscarinic Antagonists Nervous System Neurotoxic agents Neurotransmitter Agents P-glycoprotein inhibitors P-glycoprotein substrates Peripheral Nervous System Agents Phenothiazines Phenothiazines With Aliphatic Side-Chain Photosensitizing Agents Psycholeptics Psychotropic Drugs QTc Prolonging Agents Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin 5-HT1 Receptor Antagonists Serotonin 5-HT1A Receptor Antagonists Serotonin 5-HT2 Receptor Antagonists Serotonin 5-HT2A Receptor Antagonists Serotonin 5-HT2C Receptor Antagonists Serotonin Agents Serotonin Receptor Antagonists Sulfur Compounds Tranquilizing Agents

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Cross-references: BindingDB: 50001888 ChEBI: 3647 CHEMBL71 ChemSpider: 2625 Drugs Product Database (DPD): 8017 Guide to Pharmacology: 83 IUPHAR: 83 C06906 D00270 PDB: Z80 PharmGKB: PA448964 PubChem:2726 PubChem:46508395 RxCUI: 2403 Therapeutic Targets Database: DAP000374 Wikipedia: Chlorpromazine ZINC: ZINC000000044027