2-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-3-(4-methoxy-phenyl)-propan-1-ol

InChIKey	`ZOROFBCOYYIWNJ-UHFFFAOYSA-N`
Compound Name	2-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-3-(4-methoxy-phenyl)-propan-1-ol
Canonical SMILES	`COc1ccc(CC(CO)n2cc(-c3cccc(OC)c3)c3c(N)ncnc32)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	6.17
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00519	ABL1	Homo sapiens	Human	PF08919 PF07714 PF00017 PF00018	6.2	IC50	ChEMBL;BindingDB
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	6.2	pIC50	TTD_MultiTarget
P42684	ABL2	Homo sapiens	Human	PF08919 PF07714 PF00017 PF00018	6.2	IC50	ChEMBL
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	Clinical	TTD_MultiTarget	TTD_MultiTarget
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	Clinical	TTD_MultiTarget	TTD_MultiTarget