Molecule Details
InChIKeyZORLJXWXFABTPZ-CTNGQTDRSA-N
Compound Name4-(2-(Methoxymethyl)-1-((R)-1-phenylethyl)-8-((S)-pyrrolidin-3-ylmethoxy)-1H-imidazo[4,5-c]quinolin-7-yl)-3,5-dimethylisoxazole
Canonical SMILESCOCc1nc2cnc3cc(-c4c(C)noc4C)c(OC[C@H]4CCNC4)cc3c2n1[C@H](C)c1ccccc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.69
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
O60885 BRD4 Homo sapiens Human PF17035 PF17105 PF00439 7.4 IC50 ChEMBL;BindingDB
Q15059 BRD3 Homo sapiens Human PF17035 PF00439 7.4 IC50 ChEMBL;BindingDB
P13500 CCL2 Homo sapiens Human PF00048 7.1 IC50 ChEMBL
P25440 BRD2 Homo sapiens Human PF17035 PF00439 7.1 IC50 ChEMBL;BindingDB
Q58F21 BRDT Homo sapiens Human PF17035 PF17105 PF00439 6.8 IC50 ChEMBL;BindingDB
P35462 DRD3 Homo sapiens Human PF00001 6.3 Ki ChEMBL
P21917 DRD4 Homo sapiens Human PF00001 6.1 Ki ChEMBL
P02708 CHRNA1 Homo sapiens Human PF02931 PF02932 6.0 IC50 ChEMBL
P08684 CYP3A4 Homo sapiens Human PF00067 6.0 IC50 ChEMBL