Molecule Details
InChIKeyZONWPEAFLDQJPL-KKXYHZGYSA-N
Compound Name2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-5,6-dimethyl-1H-benzimidazole
Canonical SMILESCc1cc2nc([C@H]3[C@@H](c4ccc(Cl)cc4)C[C@@H]4CC[C@H]3N4C)[nH]c2cc1C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL6.8
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q01959 SLC6A3 Homo sapiens Human PF00209 8.1 IC50 ChEMBL;BindingDB
P23975 SLC6A2 Homo sapiens Human PF00209 7.7 IC50 ChEMBL;BindingDB
P08648 ITGA5 Homo sapiens Human PF01839 PF08441 PF20805 PF20806 6.2 IC50 ChEMBL
P17787 CHRNB2 Homo sapiens Human PF02931 PF02932 6.2 IC50 ChEMBL
P30926 CHRNB4 Homo sapiens Human PF02931 PF02932 6.2 IC50 ChEMBL
P32297 CHRNA3 Homo sapiens Human PF02931 PF02932 6.2 IC50 ChEMBL