Molecule Details
| InChIKey | ZOBPZXTWZATXDG-UHFFFAOYSA-N |
|---|---|
| Compound Name | Thiazolidinedione |
| Canonical SMILES | O=C1CSC(=O)N1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.27 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB11898 |
|---|---|
| Drug Name | 2,4-thiazolidinedione |
| CAS Number | 2295-31-0 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Thiazolidinedione has been investigated for the treatment of Type 2 Diabetes, Diabetes Mellitus, and DIABETES MELLITUS, TYPE 2. |
Categories: Blood Glucose Lowering Agents Ligands Sulfur Compounds Thiazoles
Cross-references: ChEBI: 50992 CHEMBL85398 ChemSpider: 5242 PDB: OD3 PubChem:5437 PubChem:347828231 ZINC: ZINC000008554292
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O43451 | MGAM | Homo sapiens | Human | PF13802 PF01055 PF21365 PF00088 | 6.3 | IC50 | ChEMBL |
| P10253 | GAA | Homo sapiens | Human | PF13802 PF01055 PF21365 PF00088 | 6.3 | IC50 | ChEMBL |
| P14410 | SI | Homo sapiens | Human | PF13802 PF01055 PF21365 PF00088 | 6.3 | IC50 | ChEMBL |
| Q2M2H8 | MGAM2 | Homo sapiens | Human | PF13802 PF01055 PF21365 PF00088 | 6.3 | IC50 | ChEMBL;BindingDB |
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P37231 | PPARG | Peroxisome proliferator-activated receptor gamma | agonist | targets |