Molecule Details
InChIKeyZOBDWFRKFSPCRB-UNMCSNQZSA-N
Canonical SMILESCCc1ccccc1NC(=O)Oc1ccc2c(c1)[C@]1(C)CCN(C)O[C@@H]1N2C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.85
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB06525
Drug NameGanstigmine
CAS Number457075-21-7
Groups experimental
ATC Codes nan
DescriptionGanstigmine is an orally active, geneserine derived, carbamate-based acetylcholinesterase inhibitor developed for the treatment of Alzheimer's disease.

Categories: Acids, Acyclic Carbamates Cholinesterase Inhibitors
Cross-references: BindingDB: 10970 CHEMBL121810 ChemSpider: 7999041 ZINC: ZINC000003814007
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P22303 ACHE Homo sapiens Human PF08674 PF00135 7.2 IC50 ChEMBL;BindingDB
P06276 BCHE Homo sapiens Human PF08674 PF00135 6.5 IC50 ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P06276 BCHE Cholinesterase inhibitor targets
P22303 ACHE Acetylcholinesterase inhibitor targets