Molecule Details
| InChIKey | ZNRNCCOAWBUSNP-BKDNQFJXSA-N |
|---|---|
| Compound Name | (1S,2S,5R)-2-[(5-chloro-3-pyridinyl)oxymethyl]-3-azabicyclo[3.1.0]hexane |
| Canonical SMILES | Clc1cncc(OC[C@H]2NC[C@@H]3C[C@@H]32)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.89 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P17787 | CHRNB2 | Homo sapiens | Human | PF02931 PF02932 | 9.7 | Ki | ChEMBL |
| P43681 | CHRNA4 | Homo sapiens | Human | PF02931 PF02932 | 9.7 | Ki | ChEMBL;BindingDB |
| P30926 | CHRNB4 | Homo sapiens | Human | PF02931 PF02932 | 8.1 | Ki | ChEMBL |
| P32297 | CHRNA3 | Homo sapiens | Human | PF02931 PF02932 | 8.1 | Ki | ChEMBL;BindingDB |