(3P)-3-[6-chloro-4-(9-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile

InChIKey	`ZNRKSAWCBMXCBN-UHFFFAOYSA-N`
Compound Name	(3P)-3-[6-chloro-4-(9-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile
Canonical SMILES	`CN1CCC2(CC1)CN(c1ncnc3[nH]c(Cl)c(-c4cccc(C#N)c4)c13)CCO2`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.63
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P24723	PRKCH	Homo sapiens	Human	PF00130 PF00168 PF00069 PF00433	8.1	Ki	ChEMBL
Q04759	PRKCQ	Homo sapiens	Human	PF00130 PF21494 PF00069 PF00433	7.5	Ki	ChEMBL
Q92918	MAP4K1	Homo sapiens	Human	PF00780 PF00069	7.3	IC50	ChEMBL