Molecule Details
| InChIKey | ZNBZVAGNLWMGJD-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[7-(5-methoxy-1H-indol-3-yl)isoquinolin-6-yl]acetamide |
| Canonical SMILES | COc1ccc2[nH]cc(-c3cc4cnccc4cc3NC(C)=O)c2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.86 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9HAZ1 | CLK4 | Homo sapiens | Human | PF00069 | 7.7 | IC50 | ChEMBL;BindingDB |
| P49759 | CLK1 | Homo sapiens | Human | PF00069 | 7.5 | IC50 | ChEMBL;BindingDB |
| Q9Y463 | DYRK1B | Homo sapiens | Human | PF00069 | 6.2 | IC50 | ChEMBL;BindingDB |
| Q13627 | DYRK1A | Homo sapiens | Human | PF00069 | 6.1 | IC50 | ChEMBL;BindingDB |