Molecule Details
| InChIKey | ZMDOIQGPLNKPIO-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(5-Chloro-2-pyridinyl)-8-[4-(4-fluorophenyl)butyl]-3,8-diazabicyclo[3.2.1]octane |
| Canonical SMILES | Fc1ccc(CCCCN2C3CCC2CN(c2ccc(Cl)cn2)C3)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.8 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P21917 | DRD4 | Homo sapiens | Human | PF00001 | 7.4 | Ki | ChEMBL |
| P08908 | HTR1A | Homo sapiens | Human | PF00001 | 7.0 | Ki | ChEMBL |
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 7.0 | Ki | ChEMBL |
| P31645 | SLC6A4 | Homo sapiens | Human | PF03491 PF00209 | 6.8 | Ki | ChEMBL |
| P34969 | HTR7 | Homo sapiens | Human | PF00001 | 6.5 | Ki | ChEMBL |
| P35462 | DRD3 | Homo sapiens | Human | PF00001 | 6.1 | Ki | ChEMBL |