Molecule Details
InChIKeyZLQKJFNLHHGAQF-IBGZPJMESA-N
Compound NameL-790070
Canonical SMILESC[C@H](Nc1cc(-c2c(-c3cccc(C(F)(F)F)c3)nc(C3CCNCC3)n2C)ccn1)c1ccccc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL8.59
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
Q15759 MAPK11 Homo sapiens Human PF00069 9.9 IC50 ChEMBL;BindingDB
O15264 MAPK13 Homo sapiens Human PF00069 9.1 IC50 ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 9.1 IC50 ChEMBL
Q16539 MAPK14 Homo sapiens Human PF00069 8.7 IC50 ChEMBL;BindingDB
P04049 RAF1 Homo sapiens Human PF00130 PF07714 PF02196 6.1 IC50 ChEMBL;BindingDB