N-propyl-4-[[4-(3,3,3-trifluoropropyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]benzamide

InChIKey	`ZLLCVOJWNDZXIO-UHFFFAOYSA-N`
Compound Name	N-propyl-4-[[4-(3,3,3-trifluoropropyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]benzamide
Canonical SMILES	`CCCNC(=O)c1ccc(Nc2nc(CCC(F)(F)F)c3cc[nH]c3n2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	11
Pfam Stratification	Cross-Family
Avg pChEMBL	6.26
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q5S007	LRRK2	Homo sapiens	Human	PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477	7.3	Ki	ChEMBL
Q9HAZ1	CLK4	Homo sapiens	Human	PF00069	6.4	Ki	ChEMBL
O60674	JAK2	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	6.3	Ki	ChEMBL
P35968	KDR	Homo sapiens	Human	PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854	6.3	Ki	ChEMBL
P45983	MAPK8	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
O96013	PAK4	Homo sapiens	Human	PF00786 PF00069	6.2	Ki	ChEMBL
Q04912	MST1R	Homo sapiens	Human	PF07714 PF01437 PF01403 PF01833	6.1	Ki	ChEMBL
P07333	CSF1R	Homo sapiens	Human	PF00047 PF25305 PF07714	6.0	Ki	ChEMBL
P07949	RET	Homo sapiens	Human	PF00028 PF07714 PF17756 PF17812 PF17813 PF22540	6.0	Ki	ChEMBL
Q00535	CDK5	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL
Q96GD4	AURKB	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL