Molecule Details
| InChIKey | ZKWWEOIHGRQYDB-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-({4-[(5-methyl-1H-indazol-4-yl)amino]pyrimidin-2-yl}amino)benzene-1-sulfonamide |
| Canonical SMILES | Cc1ccc2[nH]ncc2c1Nc1ccnc(Nc2cccc(S(N)(=O)=O)c2)n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.6 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q06187 | BTK | Homo sapiens | Human | PF00779 PF00169 PF07714 PF00017 PF00018 | 7.2 | IC50 | ChEMBL |
| P42681 | TXK | Homo sapiens | Human | PF07714 PF00017 PF00018 | 6.7 | IC50 | ChEMBL |
| P07948 | LYN | Homo sapiens | Human | PF07714 PF00017 PF00018 | 6.4 | IC50 | ChEMBL |
| P43405 | SYK | Homo sapiens | Human | PF07714 PF00017 | 6.2 | IC50 | ChEMBL |