Molecule Details
| InChIKey | ZKQWBIBGYRHIPV-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-[2-[4-[2-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-3H-benzimidazol-5-yl]pyrazol-1-yl]ethyl]morpholine |
| Canonical SMILES | COc1cc(CCc2cc(-c3nc4ccc(-c5cnn(CCN6CCOCC6)c5)cc4[nH]3)n[nH]2)cc(OC)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.37 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P21802 | FGFR2 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 8.0 | IC50 | ChEMBL;BindingDB |
| P11362 | FGFR1 | Homo sapiens | Human | PF07679 PF00047 PF07714 | 7.4 | IC50 | ChEMBL;BindingDB |
| P22607 | FGFR3 | Homo sapiens | Human | PF21165 PF07679 PF13927 PF07714 | 6.8 | IC50 | ChEMBL;BindingDB |