Molecule Details
InChIKeyZKLWHHZNVMVOLN-UKMWPXLWSA-N
Canonical SMILESC=CC(=O)N1CCC[C@]2(C1)C[C@H](n1c(NC(=O)c3ccc(C(F)F)s3)nc3cc(CN[C@@H](C)C(C)(C)C)ccc31)C2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL9.43
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P42681 TXK Homo sapiens Human PF07714 PF00017 PF00018 9.7 IC50 ChEMBL;BindingDB
Q08881 ITK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 9.2 IC50 ChEMBL;BindingDB