(S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 4,4,4-trifluoro-butyl ester

InChIKey	`ZJYCLDORACELQK-AYLZSAKASA-N`
Compound Name	(S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 4,4,4-trifluoro-butyl ester
Canonical SMILES	`COc1ccc([P@@](=O)(OCCCC(F)(F)F)N2Cc3ccccc3C[C@@H]2C(=O)NO)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.9
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P14780	MMP9	Homo sapiens	Human	PF00040 PF00045 PF00413	8.3	Ki	BindingDB
P03956	MMP1	Homo sapiens	Human	PF00045 PF00413 PF01471	7.9	Ki	ChEMBL;BindingDB
P08254	MMP3	Homo sapiens	Human	PF00045 PF00413 PF01471	7.5	Ki	BindingDB