Molecule Details
| InChIKey | ZJXIUGNEAIHSBI-IBGZPJMESA-N |
|---|---|
| Compound Name | N-(((2S)-1-((5-(4-Fluorophenyl)-2-methyl-4-thiazolyl)carbonyl)-2-piperidinyl)methyl)-4-benzofurancarboxamide |
| Canonical SMILES | Cc1nc(C(=O)N2CCCC[C@H]2CNC(=O)c2cccc3occc23)c(-c2ccc(F)cc2)s1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 9.45 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB14822 |
|---|---|
| Drug Name | SB-649868 |
| CAS Number | 380899-24-1 |
| Groups | investigational |
| ATC Codes | nan |
| Description | SB-649868 is under investigation in clinical trial NCT01030939 (Study to Investigate Safety, Tolerability, Pharmacokinetics and Cardiac Function After Repeat Doses of SB-649868 in Healthy-volunteers). |
Categories: Carbon Radioisotopes Heterocyclic Compounds, Fused-Ring Sulfur Compounds
Cross-references: BindingDB: 50417257 CHEMBL1272307 ChemSpider: 25069706 Wikipedia: SB-649868
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| O43613 | HCRTR1 | Orexin/Hypocretin receptor type 1 | antagonist | targets |