Molecule Details
| InChIKey | ZJKIGHOTHYACFW-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-N-[5-(2,4-difluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-2-methylpropane-1,2-diamine |
| Canonical SMILES | CC(C)(N)CNc1nn2c(-c3ccc(F)cc3F)cnc2s1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.01 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q8TF76 | HASPIN | Homo sapiens | Human | PF12330 | 8.0 | IC50 | ChEMBL |
| P36888 | FLT3 | Homo sapiens | Human | PF00047 PF07714 | 7.0 | Kd | ChEMBL |
| Q86V86 | PIM3 | Homo sapiens | Human | PF00069 | 7.0 | Kd | ChEMBL |
| P11309 | PIM1 | Homo sapiens | Human | PF00069 | 6.7 | Kd | ChEMBL |
| P50613 | CDK7 | Homo sapiens | Human | PF00069 | 6.7 | Kd | ChEMBL |
| Q9P1W9 | PIM2 | Homo sapiens | Human | PF00069 | 6.7 | Kd | ChEMBL |