N-(2-(diethylamino)ethyl)-3-(4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)benzamide

InChIKey	`ZJCKMANGHDJUQT-UHFFFAOYSA-N`
Compound Name	N-(2-(diethylamino)ethyl)-3-(4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)benzamide
Canonical SMILES	`CCN(CC)CCNC(=O)c1cccc(Nc2nccc(-c3cnn4ncccc34)n2)c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.73
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P11802	CDK4	Homo sapiens	Human	PF00069	8.1	IC50	ChEMBL;BindingDB
P49841	GSK3B	Homo sapiens	Human	PF00069	7.7	IC50	ChEMBL;BindingDB
P24941	CDK2	Homo sapiens	Human	PF00069	7.4	pIC50	TTD_MultiTarget